Since AMPATH’s inception, Health Information Technology (HIT) has been identified as a key innovation that drives and directly supports the healthcare mission. As AMPATH evolves into a broader health systems strengthening initiative, the AMPATH Informatics team sees a unique opportunity to not only directly support this broader mandate, but also serve as an international “proof of concept” for resource-constrained environments throughout the world. The mission of the AMPATH Informatics department is to provide effective and innovative information technology to support and drive the ongoing mission of AMPATH in Western Kenya.